Myocardial hibernation and stunning: from physiological principles to clinical practice
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چکیده
منابع مشابه
Myocardial hibernation and stunning: from physiological principles to clinical practice.
In patients with coronary artery disease, one of the most powerful determinants of prognosis is left ventricular function. 2 Thus, if we assume that the prognostic benefit of revascularisation is mediated through an eVect on left ventricular function, two mechanisms might explain this benefit. First, coronary artery bypass surgery or angioplasty could reduce the impact of coronary artery diseas...
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The last 3 decades have witnessed an unprecedented improvement in the outcome of patients with acute coronary syndromes. The widespread use of thrombolytic therapy and percutaneous coronary interventions, in association with increasingly potent antithrombotic agents, has contributed to significant reductions in mortality and morbidity in these patients. Although overall survival has improved, a...
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Correspondence to: Don Poldermans, MD, PhD, Thoraxcentre, Department of Cardiology, Erasmus Medical Centre Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands; [email protected] _________________________ C oronary artery disease is the most common cause of congestive heart failure. More than 70% of the patients with heart failure symptoms have underlying coronary diseas...
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Principle 7: Most Therapies Produce a Combination of Helpful and Harmful Effects As therapies have become more biologically potent, it has become increasingly clear that every treatment can be harmful in some patients while being beneficial in others, and often both good and bad effects occur in the same patient. With many therapies, clinical characteristics can identify patients with greater e...
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The first 2 parts of this review discussed lessons learned from cardiovascular clinical trials about the design and interpretation of clinical trials. In the next 2 parts, we will attempt to apply these lessons to decision-making in clinical practice. We undertake this effort with trepidation, recognizing that translating research findings into the care of an individual patient is a frontier th...
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ژورنال
عنوان ژورنال: Heart
سال: 1998
ISSN: 1355-6037
DOI: 10.1136/hrt.80.3.218